Particle Size Distribution and Chemical Composition of the Aerosolized Vitamin E Acetate

Vladimir B Mikheev, Theodore P Klupinski, Alexander Ivanov, Eric A Lucas, Erich D Strozier, Cory Fix

Aerosol Sci Technol . 2020;54(9):993-998. doi: 10.1080/02786826.2020.1783431. Epub 2020 Jul 7.

Introduction

The recent e-cigarette, or vaping, product use–associated lung injury (EVALI) crisis led to hospitalization and death in US youth and young adults (Blount et al. 2020US FDA 2019). Most EVALI cases were apparently linked to the vaping of e-liquids that contained vitamin E acetate (VEA) and tetrahydrocannabinol (THC) (Blount et al. 2020). At the same time, not all vapers who inhaled VEA- or THC-containing aerosol have developed EVALI symptoms, therefore other factors, such as an individual’s health status, differences in puffing behaviors, or types of vaping devices, may be important.

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Vitamin E as promising adjunct treatment option in the combat of infectious diseases caused by bacterial including multi-drug resistant pathogens – Results from a comprehensive literature survey

Minnja S Hartmann, Soraya Mousavi, Stefan Bereswill, Markus M Heimesaat

Eur J Microbiol Immunol (Bp) . 2020 Nov 5. doi: 10.1556/1886.2020.00020. Online ahead of print.

Abstract

The use of antibiotics has provoked an emergence of various multidrug-resistant (MDR) bacteria. Infectious diseases that cannot be treated sufficiently with conventional antibiotic intervention strategies anymore constitue serious threats to human health. Therefore, current research focus has shifted to alternative, antibiotic-independent therapeutic approaches. In this context, vitamin E constitutes a promising candidate molecule due to its multi-faceted modes of action. Therefore, we used the PubMed database to perform a comprehensive literature survey reviewing studies addressing the antimicrobial properties of vitamin E against bacterial pathogens including MDR bacteria. The included studies published between 2010 and 2020 revealed that given its potent synergistic antimicrobial effects in combination with distinct antibiotic compounds, vitamin E constitutes a promising adjunct antibiotic treatment option directed against infectious diseases caused by MDR bacteria such as Pseudomonas aeruginosa, Burkholderia cenocepacia and methicillin-resistant Staphylococcus aureus (MRSA). In conclusion, the therapeutic value of vitamin E for the treatment of bacterial infections should therefore be investigated in future clinical studies.

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Ophthalmologic evaluation in vitamin-E deficiency: A case report

Daniele Sindaco, Francesca Cappelli, Aldo Vagge, Carlo E Traverso, Michele Iester

Eur J Ophthalmol . 2020 Nov 3;1120672120970112. doi: 10.1177/1120672120970112. Online ahead of print.

Abstract

A 41-year-old woman has come to our attention complaining of decreased visual acuity and monocular diplopia associated with upper and lower limb hypoesthesia. Malabsorption syndrome with vitamin A and E deficiency developed after a bariatric biliopancreatic diversion. The clinical ophthalmological signs and symptoms improved after oral vitamin supplementation therapy. The past medical history is essential in the case of a patient complaining of visual symptoms compatible with vitamin deficiency in order to detect the cause and to start a prompt therapy to avoid irreversible neurological and visual sequelae. The clinical features of our case closely resemble other cases described in the literature of patients affected by vitamin A and E deficiency secondary to malabsorption syndrome.

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Assessing the Impact of Oil Types and Grades on Tocopherol and Tocotrienol Contents in Vegetable Oils with Chemometric Methods

Yunqi Wen, Lili Xu, Changhu Xue, Xiaoming Jiang, Zihao Wei

Molecules . 2020 Nov 1;25(21):E5076. doi: 10.3390/molecules25215076.

Abstract

The consumption of vegetable oil is an important way for the body to obtain tocols. However, the impact of oil types and grades on the tocopherol and tocotrienol contents in vegetable oils is unclear. In this study, nine types of traditional edible oils and ten types of self-produced new types of vegetable oil were used to analyze eight kinds of tocols. The results showed that the oil types exerted a great impact on the tocol content of traditional edible oils. Soybean oils, corn oils, and rapeseed oils all could be well distinguished from sunflower oils. Both sunflower oils and cotton seed oils showed major differences from camellia oils as well as sesame oils. Among them, rice bran oils contained the most abundant types of tocols. New types of oil, especially sacha inchi oil, have provided a new approach to obtaining oils with a high tocol content. Oil refinement leads to the loss of tocols in vegetable oil, and the degree of oil refinement determines the oil grade. However, the oil grade could not imply the final tocol content in oil from market. This study could be beneficial for the oil industry and dietary nutrition.

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